Apptivate alternatives trial#

The active control group will have access to a simplified version of the app consisting exclusively of psychoeducational content. The intervention group will have access to the Motherly app.

Apptivate alternatives trial#

Methods: We will conduct a 2-arm parallel randomized controlled clinical trial in which 70 pregnant women between 16-40 years with depression will be randomized to intervention or active control. With this study, we will test the effectiveness of the Motherly app in addition to brief cognitive-behavioral therapies (CBT) to treat maternal depression. The Motherly app delivers a package of interventions, including mental health, sleep, nutrition, physical activity, social support, prenatal/postnatal support, and psychoeducational content. We created Motherly, a smartphone app designed to promote maternal mental health. In this context, smartphone-based interventions show immense potential. Psychosocial interventions require specialized professionals which are scarce, especially in low- and middle-income countries.

The use of psychiatric medications might result in developmental problems in the child, therefore must be used with caution. Preliminary quit rates compare favorably to previous trials of smoking cessation apps for the general population (ie, short-term, self-reported 30-day quit rates in the 8% to 18% range) and a previous trial of face-to-face BAT-D for depressed smokers (ie, CO-confirmed, 7-day PPA rate of 17% at end of treatment).īackground: Pregnancy is strongly associated with increased risk for depression, but treating pregnant women is challenging. Results demonstrate promising engagement with Actify! and potential for impact on theory-based change processes and cessation outcomes. Additionally, carbon monoxide (CO)-confirmed, 7-day point prevalence abstinence (PPA) at 6-week follow-up was 31% (5/16), and the 30-day PPA was 19% (3/16).

There was a significant decrease in depressive symptoms from baseline to follow-up (mean change in Patient Health Questionnaire-9 scores was -4.5, 95% CI -7.7 to -1.3 P=.01). Posttreatment interviews identified some usability challenges (eg, high perceived burden of planning and scheduling values-based activities). Regarding acceptability, average number of log-ins per participant was 16.6 (SD 13.7), and 63% (10/16) reported being satisfied overall with the app. We examined use outcomes for all enrolled participants and process and cessation outcomes at 6 weeks postenrollment for study completers (16/17, 94% retention). Participants in the trial were current, daily smokers with mild to moderate depressive symptoms. Participants used SmokefreeTXT along with Actify! to provide cessation content that had not yet been built into the app for this initial phase of pilot testing. The aims of the study were to develop a BAT-D mobile health app with high potential reach and determine its feasibility, acceptability, and preliminary effects on theory-based behavioral processes of behavioral activation, reduced depressive symptoms, and smoking cessation.įollowing a user-centered design process consisting of competitive analysis, focus groups, and prototype testing, we conducted a single-arm pilot trial of Actify!, a BAT-D app for depressed smokers. However, this approach has only been tested as a face-to-face intervention, which has low reach. The integration of Behavioral Activation Treatment for Depression (BAT-D) into smoking cessation interventions is a promising approach to address depression as a barrier to quitting.